'World-first' vaccine designed by AI to prevent pandemics

Artificial intelligence has been used to develop a "fundamentally new" type of vaccine that could protect against large swathes of viruses and prevent pandemics, say researchers.

The team at the University of Cambridge say it is the first time a vaccine's key component has been designed entirely by AI and then trialled in people, according to BBC.

The vaccine was engineered to work on all coronaviruses which would include all Covid variants as well as viruses that currently infect animals yet have the potential to start the next pandemic.

The work is still in the early stages, but the team is already developing separate vaccines that could tackle flu and Ebola.

Vaccines teach our bodies how to spot an infection to increase our chances of fighting it off. But some viruses are adept at changing their appearance - or mutating - so vaccines can quickly go out of date. It's why Covid and winter flu vaccines need to be regularly updated.

"We're always behind," said Prof Jonathan Heeney, from the University of Cambridge, adding "what we're trying to do is get ahead of the curve" and so far ahead they could protect against new outbreaks or pandemics. Normally vaccines are designed using a current strain of a virus.

The Cambridge researchers took known genetic codes - the instruction manuals of life - from a range of coronaviruses that had been recorded by surveillance programmes hunting for potential viral threats.

These genetic codes were analysed by an artificial intelligence. It then designed a "super-antigen" that could train the immune system in such a way it gave protection against the whole family of viruses - even if they mutated or a new infection jumped from animals to people.