US President Barack Obama has backed India's entry into the Missile Technology Control Regime (MTCG) and Nuclear Suppliers Group (NSG).
India's entry into these groups will give it easier access to technology for research and advancement.
President Obama made the statement at a meeting with India Prime Minister Narendra Modi in Washington.
The two leaders also signed agreements to boost co-operation in trade, military ties and climate change.
Mr Modi and Mr Obama also signed an agreement to enable US-based Westinghouse Electric Co to start building six reactors in India.
The US and India will "remain invested in each other's prosperity", they said.
Tuesday's meeting was Mr Modi's seventh with Mr Obama since becoming prime minister in 2014.
A joint statement issued after the meeting said both countries "share common climate and clean energy interests" and are "close partners" in the fight against global warming.
The leaders also promised to ratify the Paris Agreement in their respective countries "as soon as possible this year".
India is the world's third-largest greenhouse gas emitter after China and the United States.
"Noting that the US-India defence relationship can be an anchor of stability and given the increasingly strengthened co-operation in defence, the United States hereby recognises India as a major defence partner," the statement read.
Next on the agenda for the Indian prime minister is an address to a joint session of the US Congress on Wednesday.
Analysts say that the speech is significant because it "completes the circle of rehabilitation" for him.