
Natalie Portman is starring in the movie and Gina Rodriguez is among those in the case of the project, which is an adaptation of a book by Jeff VanderMeer.
The story follows a biologist, to be played by Portman, as she embarks on a four-person expedition into Area X, a territory cut off from civilization. While there, she must deal with a mysterious contamination, disappearing colleagues, a deadly animal and a being known as the Crawler, all while searching for clues regarding her husband's disappearance.
Isaac will play Portman's husband, who may not have disappeared after all.
Scott Rudin is producing the project.
Isaac starred with Alicia Vikander and Domhnall Gleeson in Ex Machina, in which he played the Steve Jobs-like owner of a search engine tech company creating artificial intelligence.
Star Wars: The Force Awakens, meanwhile, blasted box office records and currently has grossed over $933 million domestically, $2 billion worldwide.
Isaac is repped by UTA and Inspire Entertainment. ?Hollywood Reporter